{"id":163,"date":"2022-01-13T11:23:57","date_gmt":"2022-01-13T11:23:57","guid":{"rendered":"https:\/\/revisamed.com.br\/blog-wp-teste\/2022\/01\/13\/artigo-cientifico-arritmias-cardiacas-morte-cardiovascular-e-niveis-de-potassio\/"},"modified":"2023-05-11T18:48:58","modified_gmt":"2023-05-11T18:48:58","slug":"artigo-cientifico-arritmias-cardiacas-morte-cardiovascular-e-niveis-de-potassio","status":"publish","type":"post","link":"https:\/\/revisamed.com.br\/blog\/artigo-cientifico-arritmias-cardiacas-morte-cardiovascular-e-niveis-de-potassio\/","title":{"rendered":"Artigo Cient\u00edfico: arritmias card\u00edacas, morte cardiovascular e n\u00edveis de pot\u00e1ssio"},"content":{"rendered":"<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" loading=\"lazy\" src=\"https:\/\/revisamed.com.br\/blog\/wp-content\/uploads\/2022\/01\/03646da69d248518-arritmia.png\" alt=\"Artigo Cient\u00edfico: arritmias card\u00edacas, morte cardiovascular e n\u00edveis de pot\u00e1ssio\" class=\"wp-image-16464\" width=\"880\" height=\"588\"><\/figure>\n<\/div>\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_85 counter-flat ez-toc-counter ez-toc-custom ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">A seguir, voc\u00ea vai saber:<\/p>\n<p><span class=\"ez-toc-title-toggle\"><\/span><\/div>\n<nav>\n<ul class=\"ez-toc-list ez-toc-list-level-1 \">\n<li class=\"ez-toc-page-1\"><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/revisamed.com.br\/blog\/artigo-cientifico-arritmias-cardiacas-morte-cardiovascular-e-niveis-de-potassio\/#Niveis_de_potassio_serico_arritmias_cardiacas_e_mortalidade_apos_infarto_do_miocardio_sem_elevacao_de_ST_ou_angina_instavel_insights_do_MERLIN-TIMI_36\">N\u00edveis de pot\u00e1ssio s\u00e9rico, arritmias card\u00edacas e mortalidade ap\u00f3s infarto do mioc\u00e1rdio sem eleva\u00e7\u00e3o de ST ou angina inst\u00e1vel: insights do MERLIN-TIMI 36<\/a><\/li>\n<li class=\"ez-toc-page-1\"><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/revisamed.com.br\/blog\/artigo-cientifico-arritmias-cardiacas-morte-cardiovascular-e-niveis-de-potassio\/#Introducao\">Introdu\u00e7\u00e3o:<\/a><\/li>\n<li class=\"ez-toc-page-1\"><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/revisamed.com.br\/blog\/artigo-cientifico-arritmias-cardiacas-morte-cardiovascular-e-niveis-de-potassio\/#Metodos\">M\u00e9todos:<\/a><\/li>\n<li class=\"ez-toc-page-1\"><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/revisamed.com.br\/blog\/artigo-cientifico-arritmias-cardiacas-morte-cardiovascular-e-niveis-de-potassio\/#Resultados\">Resultados:<\/a><\/li>\n<li class=\"ez-toc-page-1\"><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/revisamed.com.br\/blog\/artigo-cientifico-arritmias-cardiacas-morte-cardiovascular-e-niveis-de-potassio\/#Conclusoes\">Conclus\u00f5es:<\/a><\/li>\n<\/ul>\n<\/nav>\n<\/div>\n<h2 class=\"wp-block-heading\" id=\"h-niveis-de-potassio-serico-arritmias-cardiacas-e-mortalidade-apos-infarto-do-miocardio-sem-elevacao-de-st-ou-angina-instavel-insights-do-merlin-timi-36\"><span class=\"ez-toc-section\" id=\"Niveis_de_potassio_serico_arritmias_cardiacas_e_mortalidade_apos_infarto_do_miocardio_sem_elevacao_de_ST_ou_angina_instavel_insights_do_MERLIN-TIMI_36\"><\/span>N\u00edveis de pot\u00e1ssio s\u00e9rico, arritmias card\u00edacas e mortalidade ap\u00f3s infarto do mioc\u00e1rdio sem eleva\u00e7\u00e3o de ST ou angina inst\u00e1vel: insights do MERLIN-TIMI 36<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<h2 class=\"wp-block-heading\" id=\"h-introducao\"><span class=\"ez-toc-section\" id=\"Introducao\"><\/span><strong>Introdu\u00e7\u00e3o<\/strong>: <span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Na s\u00edndrome coronariana aguda (SCA), n\u00edveis de pot\u00e1ssio &lt;3,5 mEq \/ L est\u00e3o associados a arritmias ventriculares. As diretrizes atuais, portanto, recomendam uma meta de pot\u00e1ssio&gt; 4,0 mEq \/ L em ACS. Nosso estudo avaliou a associa\u00e7\u00e3o entre os n\u00edveis de pot\u00e1ssio, arritmias card\u00edacas e morte cardiovascular em pacientes com infarto do mioc\u00e1rdio sem supradesnivelamento do segmento ST ou angina inst\u00e1vel.<\/p>\n<h2 class=\"wp-block-heading\" id=\"h-metodos\"><span class=\"ez-toc-section\" id=\"Metodos\"><\/span><strong>M\u00e9todos<\/strong>:<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p> Os n\u00edveis de pot\u00e1ssio foram medidos em 6.515 pacientes antes da randomiza\u00e7\u00e3o para receber ranolazina ou um placebo no estudo MERLIN-TIMI 36. Uma avalia\u00e7\u00e3o eletrocardiogr\u00e1fica cont\u00ednua de sete dias foi obtida para determinar a incid\u00eancia de taquicardia ventricular n\u00e3o sustentada (TVNS) e pausas ventriculares. A associa\u00e7\u00e3o entre os n\u00edveis de pot\u00e1ssio e morte cardiovascular foi avaliada usando um modelo de regress\u00e3o de riscos proporcionais de Cox com ajuste multivari\u00e1vel.<\/p>\n<h2 class=\"wp-block-heading\" id=\"h-resultados\"><span class=\"ez-toc-section\" id=\"Resultados\"><\/span><strong>Resultados<\/strong>: <span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>NSVT com dura\u00e7\u00e3o de pelo menos oito batimentos consecutivos ocorreu mais frequentemente em n\u00edveis de pot\u00e1ssio &lt;3,5 mEq \/ L do que em n\u00edveis de pot\u00e1ssio \u2a7e5 mEq \/ L (10,1 vs. 4,5%, p = 0,03 para tend\u00eancia), enquanto o padr\u00e3o inverso foi observado para pausas ventriculares&gt; 3 s, que ocorreram mais frequentemente em n\u00edveis de pot\u00e1ssio \u2a7e5 mEq \/ L do que em n\u00edveis de pot\u00e1ssio &lt;3,5 mEq \/ L (5,9 vs. 2,0%, p = 0,03 para tend\u00eancia). Havia uma rela\u00e7\u00e3o em forma de U entre o n\u00edvel de pot\u00e1ssio na admiss\u00e3o e o risco precoce e tardio de morte cardiovascular. Em compara\u00e7\u00e3o com pacientes com n\u00edveis de pot\u00e1ssio de 3,5 a &lt;4 mEq \/ L, um n\u00edvel de pot\u00e1ssio &lt;3,5 mEq \/ L foi associado a um risco aumentado de morte cardiovascular no dia 14 (2,4 vs. 0,8%, HR adj 3,1, p = 0,02) e em um ano (6,4 vs. 3,0%, HR adj2,2, p = 0,01). O risco de morte cardiovascular em um ano tamb\u00e9m aumentou significativamente em n\u00edveis de pot\u00e1ssio \u2a7e4,5 mEq \/ L e uma tend\u00eancia semelhante foi observada em n\u00edveis de pot\u00e1ssio \u2a7e5 mEq \/ L.<\/p>\n<h2 class=\"wp-block-heading\" id=\"h-conclusoes\"><span class=\"ez-toc-section\" id=\"Conclusoes\"><\/span><strong>Conclus\u00f5es<\/strong>: <span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>O menor risco de morte cardiovascular foi observado em pacientes com n\u00edveis de pot\u00e1ssio na admiss\u00e3o entre 3,5 e 4,5 mEq \/ L. Tanto os n\u00edveis mais baixos como os mais elevados de pot\u00e1ssio foram associados a taquiarritmias e bradiarritmias, sugerindo uma potencial explica\u00e7\u00e3o mecanicista para o risco aumentado de morte cardiovascular nos extremos da homeostase do pot\u00e1ssio.<\/p>\n<p>Patel RB, Tannenbaum S, Viana-Tejedor A, Guo J, Im K, Morrow DA, Scirica BM. Serum potassium levels, cardiac arrhythmias, and mortality following non-ST-elevation myocardial infarction or unstable angina: insights from MERLIN-TIMI 36. Eur Heart J Acute Cardiovasc Care. 2017 Feb;6(1):18-25. doi: 10.1177\/2048872615624241. Epub 2016 Sep 20. PMID: 26714972; PMCID: PMC5410890. <\/p>\n<p>Confira o artigo na integra <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26714972\/\" target=\"_blank\" rel=\"noopener noreferrer\">clicando aqui<\/a>.<\/p>\n<hr class=\"wp-block-separator\">\n<p>Leia tamb\u00e9m: <\/p>\n<figure class=\"wp-block-embed is-type-wp-embed is-provider-revisamed wp-block-embed-revisamed\">\n<div class=\"wp-block-embed__wrapper\">\n<blockquote class=\"wp-embedded-content\" data-secret=\"aSbtxbjAyQ\"><p><a href=\"https:\/\/revisamed.com.br\/blog\/smartwatch-identifica-arritmias-cardiacas\/\">Artigo Cient\u00edfico: smartwatch  pode identificar arritmias card\u00edacas?<\/a><\/p><\/blockquote>\n<p><iframe src=\"https:\/\/medprovas.com.br\/blog\/smartwatch-identifica-arritmias-cardiacas\/embed\/#?secret=qdxcUCX01o#?secret=aSbtxbjAyQ\" title=\"\u201cArtigo Cient\u00edfico: smartwatch pode identificar arritmias card\u00edacas?\u201d \u2014 Revisamed\" class=\"wp-embedded-content\" width=\"600\" height=\"338\" frameborder=\"0\" loading=\"lazy\" referrerpolicy=\"strict-origin-when-cross-origin\"><\/iframe>\n<\/div>\n<\/figure>\n<nav class=\"post-tags\" aria-label=\"Tags do conte\u00fado\"><a href=\"\/tag\/cardiologia\/\">Cardiologia<\/a><a href=\"\/tag\/especialidades-medicas\/\">especialidades m\u00e9dicas<\/a><\/nav>\n","protected":false},"excerpt":{"rendered":"<p>Estudo avalia associa\u00e7\u00e3o entre n\u00edveis de pot\u00e1ssio, arritmias e morte cardiovascular em  infarto do mioc\u00e1rdio. Leia.<\/p>\n","protected":false},"author":2,"featured_media":164,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[32,24],"rvm_specialty":[],"class_list":["post-163","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","tag-cardiologia","tag-especialidades-medicas"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v28.7 (Yoast SEO v28.7) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Artigo Cient\u00edfico: arritmias card\u00edacas, morte cardiovascular e n\u00edveis de pot\u00e1ssio | Blog Revisamed<\/title>\n<meta name=\"description\" content=\"Estudo avalia associa\u00e7\u00e3o entre n\u00edveis de pot\u00e1ssio, arritmias e morte cardiovascular em infarto do mioc\u00e1rdio. 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